As of late’s publication is extra technical than standard. Should you love knowledge, you’ll revel in this deep dive—it exposes probably the most largest myths in oral well being at the moment.
For many who choose the plain-English model, right here’s a easy breakdown of what you’ll be informed:
- The “10% nano-hydroxyapatite” declare is a fable.
- A brand new peer-reviewed find out about when compared Fygg’s 3.1% nano-Hydroxyapatite method in opposition to Boka, Risewell, Simply Elements, Dr. Jen, Crest Hollow space Coverage, and ClinPro 5000 (a prescription-strength 5000 ppm fluoride toothpaste).
- High quality of debris—no longer amount—makes the adaptation.
- An excessive amount of nHA clumps, reduces teeth binding, and works much less successfully.
There’s a humorous factor that occurs on this planet of well being…
Any individual misreads the science, then turns that misinterpretation right into a advertising slogan, and ahead of you realize it, everybody’s treating it like gospel.
We’ve noticed this film ahead of. Nina Teicholz’s The Giant Fats Marvel is a living proof: early misinterpretations of diet analysis—like blaming nutritional fats for middle illness—had been enshrined in legitimate pointers and amplified via advertising.
That many years‑lengthy detour into low‑fats recommendation fueled weight problems, diabetes, and middle illness. A great instance of the way unhealthy science interpretation killed numerous folks.
On the planet of hydroxyapatite toothpastes, that slogan has grow to be: “It must be 10% nano-hydroxyapatite—or it doesn’t paintings.” And it’s flat out incorrect.
Instagram influencers parroted the ten% factor like gospel. One model constructed its entire identification round that quantity. Some even implied that in case your toothpaste didn’t hit that quantity, it wasn’t doing anything else in any respect.
For a cut up 2d, I 2d‑guessed our method at Fygg. I requested colleagues and critics to turn me the research that supposedly proved the ten% declare. Time and again, the proof didn’t grasp up.
The deeper I seemed, and the extra I spoke to the biochemists and oral microbiome scientists, the extra insane the ten% declare looked to be. As a result of in case you’ve spent sufficient time within the science—actually checked out how the oral microbiome works, how mineral debris behave within the mouth—you recognize: extra isn’t at all times higher.
If truth be told, an excessive amount of nano-hydroxyapatite (nHA) can in fact paintings in opposition to you.
Right here’s why I’m writing about this these days—because of a brand-new, peer-reviewed, Fygg-funded find out about, we after all have the information to turn precisely why that call used to be the suitable one.
Simply printed within the Magazine of Dentistry (2025), this in vitro find out about examined 8 main remineralizing toothpastes—together with fluoride, nano-HAP, micro-HAP, and sure, a well known “10% nano-HAP” model.
Direct from the find out about: “The awesome efficacy of Fygg over Dr. Jen and Risewell is most likely resulting from its enhanced physicochemical homes, relatively than just the focus of energetic components. Against this, relating to Boka, Fygg’s awesome efficiency would possibly essentially end result from the upper focus of nanoXIM in its formula.”
And it did that the use of simply 3.1% nano-hydroxyapatite.
Much more hanging: Fygg toothpaste carried out on par with prescription‑power fluoride toothpaste—the gold same old for remineralization, frequently $20-27 and best to be had with a health care provider’s prescription.
How can that be?
Why Extra Isn’t Higher
You’ll’t simply stay including extra and be expecting higher effects. If truth be told, an excessive amount of nHA can result in aggregation (it gained’t dissolve so it begins clumping into large chunks)—which decreases how smartly it disperses around the teeth floor, reduces bioavailability, and as proved via the find out about, reduces talent to opposite cavities.
“Particle dimension and formula design seem to play a pivotal function within the healing end result… The awesome efficacy of Fygg used to be most likely because of its optimized particle morphology and decrease focus of nanoXIM.” (Magazine of Dentistry, 2025)
I recognize that quote and this is a part of our secret sauce, however there’s extra to the method than that—I will move into this in additional element in a long term publication, if people have an interest. We had been searching for the suitable focus of nano-Hydroxyapatite in saliva, for it to be saved in saliva ahead of it’s taken up via the teeth. Clumping or “clogging” the saliva doesn’t paintings smartly—it’s like including an excessive amount of salt to water and a few of it doesn’t dissolve.
NanoXIM is a proprietary mix of nHA engineered at simply the suitable dimension—smaller than 50nm, with an exact rod-shaped morphology—designed to imitate herbal teeth.
Why the ten% Declare Is Unsuitable
The ten% quantity is in line with a 2009 and 2011 find out about from China when, again then, the medical group had no longer but outlined the scale of “nano” and the uniformity and purity.
10% used to be the bottom threshold at which crude samples of nano-hydroxyapatite began to turn a measurable impact. However generation has moved on. Particle morphology, floor rate, supply medium—all of that issues greater than brute focus. Numerous manufacturers in the market are the use of micro-sized debris, and the uptake of micro is solely not so good as nano.
Sadly in that crude pattern had been items of nano hydroxyapatite that don’t have compatibility the present SCCS pointers for protection. (that’s a unique argument however what they’re doing is doping the method, making it much less protected, when 2 and three% works simply wonderful IF it’s natural and top of the range).
Fygg makes use of 20% NanoXIM paste, which incorporates 15.5% nHA, leading to a three.1% general energetic nHA—and that used to be confirmed to be simpler than the overall 10% in different pastes.
“HAP debris higher than 1.3 μm have restricted adhesion to teeth, whilst the ones beneath this threshold show off sturdy floor binding… Standard micro-HAPs steadily include debris exceeding 5 µm, which display little to no efficient teeth adhesion.” (Magazine of Dentistry, 2025)
After I made up our minds I sought after to make a toothpaste, it used to be of extreme significance to me that if I used to be convincing oldsters to head fluoride-free, the other labored as smartly—if no longer higher. That intended operating with chemists, researchers, and oral microbiome professionals to seek out the precise ratio that may…
- Penetrate subsurface lesions for higher intensity of remineralization
- Steer clear of aggregation (clumping of nHAp debris making them much less efficient and to be had for remineralization)
- Appreciate the oral microbiome (the engine for remineralization)
And now, we after all have a peer-reviewed find out about to verify what chemists and scientists have identified all alongside!
It’s simple to imagine that if one thing is excellent, extra will have to be higher. However there’s at all times a candy spot with regards to metabolism and organic processes and techniques—such things as pH stability, oxygen saturation within the blood, and numerous different finely tuned purposes. An excessive amount of and too little will also be fatal in the ones two techniques.
So, it’s no longer “what’s the correct quantity for tooth” it’s “what’s the correct quantity for saliva” in order that tooth can in fact snatch it when wanted!
I’m proud Fygg led with science. And I’m thankful to the researchers who proved what we knew all alongside.
Right here’s to science, more fit mouths, and less clumps on your toothpaste.
Dr. B
P.S. Know anyone who’s parroting the ten% fable? Ahead this to them — they by no means must pass over every other publication in the event that they join long term emails right here.
